What are the key milestones that we hope to achieve in the coming years in terms of improving diagnosis, treatment, and outcomes for individuals affected by this group of disorders?

Satralizumab Recruiting Phase 3 Trials for NMDAR Autoimmune Encephalitis / Anti-Lgi-1 Associated Autoimmune Encephalitis Treatment. Back to Satralizumab ... Jan 1, 2023 ... Adverse reactions from immunotherapies occurred in 17 of 84 patients (20%). Potential contributors to misdiagnosis included overinterpretation ... A person with AE may start experiencing hallucinations and then develop seizures or problems with their memory. Nov 28, 2022 ... In this case series of 107 outpatients misdiagnosed with autoimmune encephalitis, approximately half had functional neurologic or psychiatric disorders. Autoimmune encephalitis which is where the immune system is attacking the brain, such as acute disseminated encephalomyelitis (ADEM), are caused by infection. Tumor removal is essential in most cases to remove the source of the antibodies and to improve the prognosis of the tumor itself. One study showed that 50% of ... Sep 3, 2024 ... Autoantibodies against neuronal membrane proteins can manifest in autoimmune encephalitis, inducing seizures, cognitive dysfunction and ... This article focuses on patient-centered observations, which form the foundation for accurate diagnosis of autoimmune encephalitis. Jun 16, 2020 ... Conceptual definitions for two main diagnostic entities: (a) acute symptomatic seizures secondary to autoimmune encephalitis, and (b) autoimmune-associated ... These include altered mental state, behavioural changes and agitation. They can have seizures or fits, abnormal movements, hallucinations, sleep disturbance and ...