What are the S phase checkpoints and what do they monitor?

Cells prepare for DNA replication in S phase by loading MCMs at replication origins in the preceding G1 phase, a process called “origin licensing.” The amount ... (2010). A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression. PLoS ... A cell cycle is a series of events that takes place in a cell as it grows and divides. A cell spends most of its time in what is called interphase. Background & Aims: The G1/S-phase controlling mechanism known as the RB pathway is commonly deregulated in human malignancies. Here, the abundance and ... Dec 18, 2006 ... This suppression during S phase is apparently regulated by cell cycle position alone and occurs automatically during each cell cycle. If the ... May 1, 2008 ... This indicates nuclear DNA synthesis occurs during development. Mitosis and early S phase were both twofold longer in slugs as compared with ... Jul 8, 2008 ... Cyclin D/CDdk4–Cdk6 activity occurs in mid-late G1 phase, upstream of Cdk2/cyclin E activity. Under conditions favouring proliferation, the ... Actively dividing eukaryote cells pass through a series of stages known collectively as the cell cycle: two gap phases (G1 and G2); an S (for synthesis) ... Furthermore, the cell-cycle phase may directly regulate DNA end resection as resection occurs fastest in S phase and CtIP-dependent resection is upregulated by ... Two gap phases precede the S and M phases; in G1 the cell prepares for DNA synthesis, and in G2 the cell prepares for the mitotic division that takes place in ...