What are the mechanisms for resolving stalled replication forks?

Apr 1, 2019 ... We show here that small molecule 2-[(3,4-dihydroquinolin-1(2H)-yl)(p-tolyl)methyl]phenol (THTMP), a potential anticancer agent, increases the human ... Chromosome duplication occurs during S phase of the cell cycle, whereas most other cell components are duplicated continuously throughout the cycle. During M ... Members of the Bcl-2 family play a major role in the patho-biology of head and neck cancer ... cycle and survival of endothelial cells and HNSCC and on the ... Jul 10, 2020 ... ... occurs at the K430 site (Fig. 2GOpens in ... Chen, BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle. May 13, 2018 ... Sinomenine, a bioactive alkaloid isolated from the traditional Chinese herb Sinomenium acutum, possesses antiinflammatory, antinociceptive, ... In S phase, the cell synthesizes a complete copy of the DNA in its nucleus. It also duplicates a microtubule-organizing structure called the centrosome. The ... Oct 13, 2019 ... In G1-phase cells are growing and preparing for DNA replication. The DNA replication thereafter takes place during S-phase, where the cellular ... G1 phase – cell growth · S phase – DNA synthetization · G2 phase – preparation for cell division · M phase – daughter cell formation through mitosis. There are standard modeling algorithms that can then be employed to determine the breakdown of cells in the G0/G1 phase versus S phase, G2, or polyploidy state ... Jul 29, 2019 ... Cell cycle analysis. SSCs from the control group and the heat shock-treated group (43 °C, 45 min) were seeded in 6-well plates at ...