What is the role of inflammation in the context of S phase stress and genomic instability?

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We have shown that CS exerts an inhibitory effect on the proliferation of MDA-MB-231, MCF-7 and T47D breast cancer cells in a dose and time-dependent manner. Jan 22, 2003 ... Vascular endothelial cell (VEC) proliferation is a key event in angiogenesis and is tightly regulated. Electric potential differences exist ... E.g. antimetabolites such as methotrexate work in the S phase (synthesis phase) of the cell cycle. Intravenous antineoplastic drugs are administered in the ... ... during the S-Phase of the cell cycle. Measurement of DNA synthesis is therefore essential for research in many scientific fields, such as assessing cell ... Jan 28, 2010 ... Progress in plant cell cycle research is highly dependent on reliable methods for detection of cells replicating DNA. Frequency of S-phase ... (2010). A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression. PLoS ... G1 phase – cell growth · S phase – DNA synthetization · G2 phase – preparation for cell division · M phase – daughter cell formation through mitosis. Jul 29, 2021 ... Peak Histone Biosynthesis Occurs in Early-to-Mid S Phase. Since cells aligned to anaphase will be partially out of alignment by the time they ... Background & Aims: The G1/S-phase controlling mechanism known as the RB pathway is commonly deregulated in human malignancies. Here, the abundance and ... S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication of ...
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