What are the downstream effects of this gene overexpression on other genes and proteins in the cell?

Jan 30, 2023 ... Cardiovascular disease is a leading cause of morbidity and mortality in individuals with Down syndrome. Congenital heart disease is the most ... Jul 16, 2009 ... The research sheds light on the genetic underpinnings of aneuploidy, a condition marked by having an abnormal number of chromosomes. Down syndrome, caused by meiotic separation of chromosome 21 in humans, is associated with advanced maternal age, but defining and understanding other risk ... Apr 20, 2023 ... The cause of Down syndrome is known to be an extra copy of chromosome 21, or trisomy 21. But because this chromosome contains more than 200 ... Nov 30, 2023 ... In the United States, demographic factors also affect the risk for a child to be born with Down syndrome. These factors include geographic ... Apr 12, 1994 ... In addition, Dr. Lejeune was a pioneer in clinical cytogenetics and carried out numerous clinical and biochemical studies of people with Down ... Summary · Down syndrome is a common genetic condition caused by an extra chromosome 21. · Every person with Down syndrome is an individual. · People with Down ... Down syndrome is a genetic condition caused by extra copies of chromosome 21. It results in certain characteristics, including some degree of cognitive ... Down syndrome is caused by an extra chromosome, but experts are not certain why this occurs or what factors may play a role. One factor experts do know about is ... Sometimes the extra number 21 chromosome or part of it is attached to another chromosome in the egg or sperm. This may cause translocation Down syndrome. This ...