What are the specific genes on chromosome 21 that are thought to contribute most significantly to the Down syndrome phenotype?

Mar 18, 2021 ... This additional chromosome, or portion of a chromosome, causes the common features of DS: delayed language; impaired long and short-term memory; ... Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. Down syndrome, caused by meiotic separation of chromosome 21 in humans, is associated with advanced maternal age, but defining and understanding other risk ... Aug 8, 2023 ... Down syndrome (trisomy 21) is a genetic disorder caused by the presence of all or a portion of a third chromosome 21. Mar 21, 2019 ... Get the facts on Down syndrome for World Down Syndrome Day. Learn about causes, types, and prenatal testing for informed decision-making. Jul 6, 2006 ... Article. Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration. Dermatological manifestations of Down syndrome, Trisomy 21 syndrome, Complete trisomy 21 syndrome ... What causes Down syndrome? A cell division error during ... Research and analysis Close Health topics Global Burden of Disease (GBD) study Health by location Health policy and planning Data tools and practices Trisomy 21, commonly known as Down syndrome, is a genetic disorder that causes intellectual disability, developmental delays, certain facial features, and ... What Causes Down Syndrome? Some babies are born with a condition called Down syndrome. Kids with Down syndrome often have medical problems and trouble ...