What are the challenges in developing and delivering targeted therapies for a complex condition like Down syndrome?

Jun 11, 2015 ... The most common cause of having a DS babies is presence extra copy chromosome 21 resulting in trisomy. The other causes can be Robertsonian ... “It's just a matter of catching them before they cause more difficulty.” Meet Our Experts. Down syndrome (DS) is caused by trisomy of human chromosome 21 (Hsa21) and results in a large number of phenotypes, including learning difficulties, cardiac ... Down syndrome, caused by meiotic separation of chromosome 21 in humans, is associated with advanced maternal age, but defining and understanding other risk ... Down syndrome (sometimes called Down's syndrome) is a condition in which a child is born with an extra copy of their 21st chromosome — hence its other name, ... Jul 17, 2013 ... Scientists have corrected the genetic fault that causes Down's syndrome – albeit in isolated cells – raising the prospect of a radical therapy ... Down syndrome is a genetic condition caused by extra copies of chromosome 21. It results in certain characteristics, including some degree of cognitive ... Mar 8, 2018 ... There's no doubt that an extra copy of chromosome 21 is what causes Down syndrome. There's a lot of doubt, however, over which particular ... Aug 8, 2023 ... Down syndrome (trisomy 21) is a genetic disorder caused by the presence of all or a portion of a third chromosome 21. Down syndrome is caused by an extra chromosome 21. Down syndrome affects people differently. It causes learning difficulties and health problems.