How does the extra copy of chromosome 21 influence synaptic plasticity and learning processes?

Research and analysis Close Health topics Global Burden of Disease (GBD) study Health by location Health policy and planning Data tools and practices Down syndrome is the most frequently occurring chromosomal disorder and the leading cause of intellectual and developmental delay in the US and in the world. What is Down syndrome? Down syndrome is caused by the presence of an extra chromosome number 21 in the cells of the developing baby. Jan 25, 2025 ... Here are four factors that may be associated with an increased risk of having a baby with Down syndrome. Jan 30, 2023 ... Cardiovascular disease is a leading cause of morbidity and mortality in individuals with Down syndrome. Congenital heart disease is the most ... Down's syndrome is the commonest identifiable cause of intellectual disability, accounting for around 15-20% of the intellectually disabled population. It is ... Cerebral palsy is a neurological condition that usually occurs at birth and causes physical disabilities. Down syndrome is a chromosomal abnormality that causes ... Down syndrome is caused by an extra chromosome, but experts are not certain why this occurs or what factors may play a role. One factor experts do know about is ... Oct 20, 2023 ... Down syndrome is a genetic disorder caused by an extra full or partial cell division of a human's chromosome 21, resulting in lifelong intellectual disability, ... Down syndrome is usually caused by an error in cell division called “nondisjunction.” Nondisjunction results in an embryo with three copies of chromosome 21 ...