What are the signaling pathways involved in hair cell development and regeneration?

Feb 22, 2024 ... Today's #LabVocab is stereocilia – a part of the ear that plays a critical role in how humans experience sound and balance. Jun 11, 2019 ... ... stereocilia. The stereocilia within the same hair bundle have differing lengths. They are aligned in an orderly way to form a wedge shape ... May 10, 2021 ... We show that IHC and OHC stereocilia are similarly TM-embedded and that Ca 2+ ducts connect the TM to the stereocilia of IHCs and OHCs. Aug 13, 2024 ... Within the inner ear lies the cochlea, which is your organ of hearing, and it houses tiny nerve endings called stereocilia. Sensorineural ... May 24, 2023 ... Stereocilia are vital for the transmission of sound as they house the mechanoelectrical transduction channels triggered by the bending of the ... We previously reported that CIB2 binds to WHRN and is essential for stereocilia staircase architecture of cochlear hair cells. Here, we refine the ... Mar 27, 2024 ... Using scanning electron microscopy and super-resolution microscopy, we investigate stereocilia formation from hair cell specification stages in the mouse organ ... Many experimental observations over the past decade have indicated that the role of stereocilia structure and function in cochlear hair-cell transduction is ... Mar 21, 2011 ... The mechanotransducer channels of auditory hair cells are gated by tip-links, oblique filaments that interconnect the stereocilia of the ... Mar 13, 2020 ... When stereocilia become damaged, they do not regenerate, and sensorineural hearing loss is the result. While there are no surgeries that can ...