What are the ethical considerations associated with regenerative therapies for hearing loss?

Jul 1, 1980 ... From our results, we conclude that the stereocilia of the ear, unlike the brush border of intestinal epithelial cells, are not designed to ... These results suggest that regulation of stereocilia length occurs through EPS8 and that CDH23 and PCDH15 regulate stereocilia lengthening beyond their role in ... May 10, 2021 ... We show that IHC and OHC stereocilia are similarly TM-embedded and that Ca 2+ ducts connect the TM to the stereocilia of IHCs and OHCs. Cilium (plu: cilia) is an organelle that is short and filament-like. It looks like an eyelash that protrudes from eukaryotic cells, and can be motile or non- ... This article obtains the stereocilia movement generated by basilar membrane (BM) vibration based on the positional relationship between the various structures ... The stereocilia of each hair cell are arranged in a precise geometry. This arrangement is asymmetrical and polarized because the stereocilia are arranged in ... These results provide the first direct evidence that type I hair cells have significantly more stereocilia than type II hair cells. You are studying the mechanism by which stereocilia in inner ear hair cells bend and transduce a ... staining reveals that it is located at the base of ... Bending the stereocilia away from the kinocilium hyperpolarizes the cell and results in a decrease in afferent activity. The semicircular ducts work in pairs to ... Oct 19, 2022 ... GPSM2-GNAI(GDP), in turn, imparts asymmetry to the forming stereocilia to enable sensory function in hair cells. INTRODUCTION. Hair cells (HCs) ...