What are the effects of chemotherapy drugs on hearing and stereocilia?

Oct 4, 2006 ... The staircase-shaped stereocilia bundle of the inner ear sensory hair cells detect mechanical stimuli by the activation of mechanoelectrical ... When your head moves, the endolymph moves the cupula and stimulates the stereocilia. Vertigo is a feeling of dizziness or sudden sensation of spinning when ... Jul 18, 2022 ... Espins are actin-bundling proteins that have a well-characterized role in stereocilia formation; loss of function mutations in Espin result in ... Feb 9, 2022 ... These cells possess stereocilia connected to the tectorial membrane. ... During auditory stimulation, sound waves in the cochlea cause deflection ... Jul 22, 2024 ... We conclude that stereocilia fusion is linked with the failure to maintain cellular proteostasis and with disturbances in stereociliary calcium balance. Aug 11, 2015 ... 2 Answers 2 ... Stereocilia are basically modified microvilli. They are much longer than microvilli, and lack the villin protein. According to ... Abstract. Stereocilia are actin-based protrusions on auditory and vestibular sensory cells that are required for hearing and balance. They convert physical ... Mar 11, 2019 ... The tip links are connected to stretch-activated cation channels on the tips of the stereocilia. When a sound wave vibrates the basilar membrane ... Mar 27, 2024 ... Stereocilia ... Structures and types of simple epithelia. ... Stereocilia are cylindrical immotile microvilli found on the apical surfaces of ... The actin filament bundle, which is held together by specific crossbridges, gives rigidity and exact dimensions to each stereocilium. The cuticular plate ...