How might the glycocalyx influence the mechanical sensitivity of stereocilia?

Trouble detecting soft or high-pitched sounds is often the first sign that stereocilia — the delicate hair cells that convert sound waves into electrical ... Mar 28, 2017 ... Mechanotransducer channels at the tips of sensory stereocilia of inner ear hair cells are gated by the tension of 'tip links' ... ... stereocilia? How did the authors explain inconsistencies with previous published results by Ohmori? c) What was the nature of the evidence that transduction ... The organ of Corti contains tiny hair cells with stereocilia at the ends. Stereocilia are delicate, hair-like projections that react to cochlea fluid movement. We previously reported that CIB2 binds to WHRN and is essential for stereocilia staircase architecture of cochlear hair cells. Here, we refine the ... Mar 11, 2019 ... The tip links are connected to stretch-activated cation channels on the tips of the stereocilia. When a sound wave vibrates the basilar membrane ... Feb 28, 2021 ... 1. Cilia can be motile or non-motile, whereas stereocilia are characterized by their lack of motility. 2. Stereocilia are actually more associated with ... These results provide the first direct evidence that type I hair cells have significantly more stereocilia than type II hair cells. Jan 25, 2022 ... Bending the stereocilia toward the kinocilium depolarizes the cell and results in increased afferent activity. Bending the stereocilia away from ... Apr 16, 2025 ... Stereocilia perch atop sensory hair cells in the inner ear. Source: Yoshiyuki Kawashima. Most NIHL is caused by the damage and eventual death of ...