Can these signaling pathways be targeted to promote regeneration?

Feb 9, 2022 ... These cells possess stereocilia connected to the tectorial membrane. ... During auditory stimulation, sound waves in the cochlea cause deflection ... ... stereocilia functional architecture and self-renewal. Rzadzinska AK 1 ,. Schneider ME ,. Davies C ,. Riordan GP ,. Kachar B. Author information. Affiliations. 1 ... Bending the stereocilia away from the kinocilium hyperpolarizes the cell and results in a decrease in afferent activity. The semicircular ducts work in pairs to ... Feb 28, 2021 ... 1. Cilia can be motile or non-motile, whereas stereocilia are characterized by their lack of motility. 2. Stereocilia are actually more associated with ... ... stereocilia. These stereocilia are grouped into hair bundles, and the stereocilia in each hair bundle work together to facilitate the conversion of physical ... Jan 21, 2021 ... Abstract. Inner ear hair cells detect sound-induced displacements and transduce these stimuli into electrical signals in a hair bundle that ... May 24, 2023 ... Stereocilia are vital for the transmission of sound as they house the mechanoelectrical transduction channels triggered by the bending of the ... Mar 21, 2011 ... The mechanotransducer channels of auditory hair cells are gated by tip-links, oblique filaments that interconnect the stereocilia of the ... Nov 7, 2011 ... The output of the cochlea is controlled by the bending of inner‐hair‐cell (IHC) stereocilia, but the mechanisms that produce this bending ... This article obtains the stereocilia movement generated by basilar membrane (BM) vibration based on the positional relationship between the various structures ...