What are the limitations of assessing safety and tolerability in the absence of a control group?

Jun 3, 2022 ... This open-label pilot study investigated whether practicing yoga in a class results in change in patients with alexisomia and alexithymia. Jan 17, 2025 ... ... trial with randomized controlled treatment group assignment, open-label treatment, and blinded core laboratory outcome evaluation. This study ... Mar 31, 2022 ... Different trial designs can be used by clinical researchers, with open-label trials one such design. This article will discuss what open-label trials are. A multicenter, single-arm, open-label trial of birociclib, a CDK4/6 inhibitor, as a single agent, in patients with refractory HR+/HER2- metastatic breast ... Open-label trial of Sibeprenlimab for treatment of IgAN. Research type. Research Study. Full title. A Phase 2/3, Multicenter, Open-label Trial to Evaluate the ... The Lancet Publishes Data from Phase 2, Open-Label Trial of Spinraza (Nusinersen) in Infants ... Today, Lancet published results from the Phase 2, open-label ... Search Clinical Trials ; GOG-3112 (DESTINY-Ovarian01) · A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan with Bevacizumab Versus ... Transcranial Focused Ultrasound (tFUS) offers a non-invasive method to modulate brain activity with high spatial precision, targeting thalamic nuclei associated ... Nov 2, 2023 ... Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria. Gayle Ross ... A MULTICENTER, RANDOMIZED OPEN-LABEL TRIAL COMPARING 1-DAY CESSATION OF DIRECT ORAL ANTICOAGULANTS BEFORE AND AFTER COLORECTAL POLYPECTOMY -MADOWAZU TRIAL-.