What are the challenges in measuring pain and function in open-label trials of musculoskeletal conditions?

A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope. Open-Label Trial ... An open-label trial is a type of study where both the participants and the investigators are aware of the treatment being provided. It is ... Nasal povidone-iodine may be considered as an alternative to mupirocin in a multifaceted approach to reduce SSI. Treating Foot Infections in Diabetic Patients: A Randomized, Multicenter, Open-Label Trial of Linezolid versus Ampicillin-Sulbactam/Amoxicillin-Clavulanate. A seven-week, open-label trial evaluating the safety and efficacy of a photopneumatic device for mitigating mild-to-moderate acne in healthy adolescents and ... Nov 2, 2023 ... Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria. Gayle Ross ... This is a first-in-human, Ph 1/2, open-label, multicenter dose escalation and expansion study in advanced solid tumors. Jan 17, 2025 ... ... trial with randomized controlled treatment group assignment, open-label treatment, and blinded core laboratory outcome evaluation. This study ... Jun 17, 2023 ... Treatment with amikacin liposome inhalation suspension (ALIS) improve culture conversion in patients with M abscessus pulmonary disease. Apr 25, 2024 ... "Results from this study show that patients with moderate-to-severe atopic dermatitis can strive for both little to no itch and clearer skin.” 1.