What are the challenges in blinding participants and providers in trials evaluating disease progression?

May 22, 2019 ... The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial ... Open-Label Trial pronounce term ... A type of clinical trial. In open-label trials, both the researchers and participants know which drug (or other intervention) ... Mar 8, 2024 ... This randomized open-label trial aimed to replicate this result in a sample of patients with risk factors for stroke (RFS). METHODS. Twenty ... This prospective, open-label clinical trial aimed to evaluate the tolerability and the efficacy of B cell depletion for remission induction in IgG4-RD. A MULTICENTER, RANDOMIZED OPEN-LABEL TRIAL COMPARING 1-DAY CESSATION OF DIRECT ORAL ANTICOAGULANTS BEFORE AND AFTER COLORECTAL POLYPECTOMY -MADOWAZU TRIAL-. An open-label, proof-of-concept phase II clinical trial was conducted in 10 PAP patients. The intervention consisted of two intravenous infusions of rituximab ( ... A5384 is a trial for people who have or might have tuberculous meningitis (TBM). TBM is an infectious disease that causes inflammation of the membranes that ... Jun 17, 2023 ... Treatment with amikacin liposome inhalation suspension (ALIS) improve culture conversion in patients with M abscessus pulmonary disease. Open-label trial of Sibeprenlimab for treatment of IgAN. Research type. Research Study. Full title. A Phase 2/3, Multicenter, Open-label Trial to Evaluate the ... Mar 29, 2019 ... Conclusion: ECLM administration to the pediatric patients with refractory epilepsy contributed to improvement of epileptic manifestation and ...