How does the open-label nature of a trial affect patient recruitment and retention?

A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope. Jul 9, 2021 ... Phase 1b open-label trial of afatinib plus Xentuzumab (BI 836845) in patients with EGFR mutation-positive NSCLC after progression on EGFR tyrosine kinase ... Oct 2, 2010 ... Methods. We undertook an open-label randomised phase 3 trial in men with metastatic castration-resistant prostate cancer who had received ... Nitazoxanide co-administered with atazanavir/ritonavir was safe but not better than standard of care in treating COVID-19. Transcranial Focused Ultrasound (tFUS) offers a non-invasive method to modulate brain activity with high spatial precision, targeting thalamic nuclei associated ... Dec 1, 2023 ... Neurona Therapeutics Presents New Clinical Data from First Cohort in Ongoing Phase I/II Open-Label Trial of NRTX-1001 Cell Therapy for Drug- ... In an open-label trial the identity of treatment is known to all. The double-blind trial is the optimal approach. This requires that the treatments to be ... For this reason, extreme care needs to be taken regarding how subjects are randomized in open-label trials and randomization methods should be clearly explained ... If you receive at least 1 dose of RYZ801, you will enter the Long-Term Follow-Up period following the Study Treatment Stage. During Long-Term Follow-Up, you ... MISSION: A Phase 2, Open-Label Trial to Evaluate Safety of Epcoritamab Monotherapy in Subjects with Relapsed or Refractory Diffuse Large B-Cell Lymphoma and ...