How can open-label trials be used to study the effects of autoimmune diseases?

Nasal povidone-iodine may be considered as an alternative to mupirocin in a multifaceted approach to reduce SSI. This prospective, open-label clinical trial aimed to evaluate the tolerability and the efficacy of B cell depletion for remission induction in IgG4-RD. Jul 31, 2024 ... The main aim is to test how safe and effective the medicine ILUVIEN® (190μg) is for children and adolescents, who have non-infectious ... Further analysis of scalp biopsies is pending. Microneedling may have a mild effect on hair regrowth in AGA but did not improve SALT score over six months in AA ... Oct 22, 2024 ... An open trial is a study design where participants and researchers are not blinded to the experiment (Sedgwick, 2014) . All the procedures were ... Jan 1, 2025 ... This open-label study suggests efficacy and safety of psilocybin in severe TRD and supports further study of psychedelics in this population. Oct 3, 2023 ... ENVOL is an open-label, single-arm, two-part study to evaluate the safety and transduction efficiency of systemic gene therapy with commercial ... The objective of this investigation is to assess the efficacy of coenzyme Q10 as a preventive treatment for migraine headaches. Nov 2, 2023 ... Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria. Gayle Ross ... (143) - Multicenter Open-Label Trial Evaluating the Safety, Tolerability, Efficacy and Pharmacokinetics (PK) of Tacrolimus Inhalational Powder as a Replacement ...