How can open-label trials be used to evaluate the effectiveness of digital therapeutics?

Open-label studies lack the rigor of blinded studies. Since the lack of blinding can introduce significant bias, reserve the use of open-label studies for ... This prospective, open-label clinical trial aimed to evaluate the tolerability and the efficacy of B cell depletion for remission induction in IgG4-RD. Addition of primaquine to artemisinin combination treatment did not improve elimination of parasitaemia and prevention of gametocyte carriage. Jan 8, 2020 ... The purpose of this research study is to analyze the treatment potential of tofacitinib in patients with sarcoidosis that involves the skin. Study protocol; Open access; Published: 23 June 2020. ENG-releasing subdermal implants in postpartum teenagers – an open-label trial study protocol. This project is being done to test the combination of Loncastuximab Tesirine along with a drug regimen called DA-EPOCH-R for patients with previously ... Apr 20, 2023 ... Open-label clinical trials are appropriate when randomization of treatments may be difficult, or if it's important to test long-term effects or safety profiles. Nov 9, 2020 ... A randomized, open-label controlled trial of oral favipiravir in adults hospitalized with moderate to severe COVID-19 pneumonia from June 22nd 2020 to August ... Study #2024-1042. A Phase II multicenter open-label trial of tagraxofusp (Tag) in combination with venetoclax and azacitidine (Ven/Aza) in adults with ... Nov 9, 2023 ... Conclusions. These findings suggest that prescribed medical cannabis may have minimal acute impact on cognitive function among patients with ...