What are the effects of diet and nutrition on ion channel function?

Jan 17, 2022 ... We introduce a way to synthesize a fully deuterated, 15 N labelled amino acid derivative and the possibility to polarize the 15 N by means of hydrogenation ... May 8, 2019 ... Hyperpolarization is one way living creatures maintain homestatis, constantly fine-turning their nervous and muscular functions. The crucial point of hyperpolarization is to transfer the polarization from highly polarized systems to nuclear spins. For example, the unpaired electrons in ... Potassium ions reach equilibrium when the membrane voltage is below −70 mV, so a period of hyperpolarization occurs while the K+ channels are open. The hyperpolarization-enhanced 1H‑imaging modality presented here can allow for hyperpolarized imaging without the need for low‑abundance, low‑sensitivity ... Sep 10, 2017 ... Hyperpolarization: The membrane potential gets more negative. Example: it was -70mV and now it is -90mV (now it is more negative than it just ... A hyperpolarized contrast agent indicated for use with magnetic resonance imaging (MRI) for evaluation of lung ventilation in adults and pediatric patients ... Hyperpolarization—that is, an increase in negative charge on the inside of the neuron—constitutes an inhibitory PSP, because it inhibits the neuron from firing ... Hyperpolarization suggests an ideal contrast mechanism to highlight the ubiquitous and specific function of water in physiology, biology, and materials ... Aug 11, 2023 ... We provide convincing evidence for the key role of the h-current in the suprathreshold frequency preference of human L5 cortical neurons.