How do the basal ganglia contribute to movement control and reward?

The finding that cAMP facilitates activation of HCN channels by affecting their voltage dependence suggests that the gating mechanism operated by ... Sep 10, 2017 ... Hyperpolarization: The membrane potential gets more negative. Example: it was -70mV and now it is -90mV (now it is more negative than it just ... When the neurotransmitter molecules bind to ligand-gated ion channels on the receiving cell, they may cause depolarization of that cell, causing it to undergo ... Mar 21, 2019 ... Significant hyperpolarization was seen in resting membrane potential in I/R group. There was no alteration in the general shape of the ... Oct 27, 2021 ... The hyperpolarization technique might not be optimal for detecting effects of insulin in skeletal muscle of anaesthetized animals, which is of significance for ... Hyperpolarized fumarate is a promising biosensor for carbon-13 magnetic resonance metabolic imaging. Such molecular imaging applications require nuclear ... The hyperpolarization represents 73 mV. These data and data shown in panel b ... hyperpolarization, appears to result from metabolism of the chemical ... Jul 13, 2018 ... Hyperpolarized MRI produces a strong signal showing ... The hyperpolarization boosts the signal captured by the MRI more than 10,000-fold. Perhaps even more surprising is that shining light on a photoreceptor, either a rod or a cone, leads to membrane hyperpolarization rather than depolarization ( ... Frydman is particularly enthusiastic about is nuclear hyperpolarization [4, 5]. ... hyperpolarization had been known about for 60 years, and for the first 40 of ...