How can we translate basic research findings on hyperpolarization into effective treatments for human diseases?

movement of a cell's membrane potential to a more negative value (i.e., movement further away from zero). When a neuron is hyperpolarized, it is less likely to ... This article reviews the latest studies concerning the characterization of endothelium-derived hyperpolarizing factors, the mechanisms of factor release and ... Jan 18, 2016 ... being more sensitive, but the transient character of the hyperpolarization requires a continuous and homogeneous supply of polarized gas ... Apr 4, 2022 ... Apparently the sodium potassium pump restores it following hyperpolarization, but I really can't imagine how it would do that! Hyperpolarization is a lowered membrane potential caused by the efflux of potassium ions and closing of the potassium channels. Resting state is when ... Hyperpolarization MRI is a newly emerging technology with potentially transformative benefits for patients. This technology relies on dramatic amplification of ... Dec 4, 2017 ... We propose that these intracellular pathways are potential therapeutic targets for achieving depolarization/hyperpolarization (D/H) balance in psychiatric and ... 4 days ago ... 2 meanings: British → a variant spelling of hyperpolarize biology, physics to cause increased polarization.... Click for more definitions. hyperpolarization, but what is the mechanism by which pinacidil causes the hyperpolarization? As described by the Goldman [11] equation, the membrane ... Hyperpolarization suggests an ideal contrast mechanism to highlight the ubiquitous and specific function of water in physiology, biology, and materials ...