Are there age-related changes in ion channel function?

May 8, 2014 ... 2.2 Hyperpolarized xenon and optical pumping. Hyperpolarization of a gas is the state where a fraction of the spins of the nuclei in the gas ... Mitochondrial hyperpolarization (MHP), an early event of T-cell activation and death, appears to be mediated through inhibition of F0F1-ATPase or ... Jan 18, 2016 ... being more sensitive, but the transient character of the hyperpolarization requires a continuous and homogeneous supply of polarized gas ... Apr 4, 2022 ... Apparently the sodium potassium pump restores it following hyperpolarization, but I really can't imagine how it would do that! Mar 16, 2022 ... Accurate simulations show astonishingly rich and unexpected dynamics in SABRE/X-SABRE, which we explain with a combination of perturbation theory and average ... Aug 11, 2023 ... We provide convincing evidence for the key role of the h-current in the suprathreshold frequency preference of human L5 cortical neurons. A hyperpolarized contrast agent indicated for use with magnetic resonance imaging (MRI) for evaluation of lung ventilation in adults and pediatric patients ... Mar 27, 2023 ... Hyperpolarized 13C MRI is an emerging powerful molecular imaging strategy that allows safe, non-radioactive, real time and pathway-specific ... Hyperpolarized fumarate is a promising biosensor for carbon-13 magnetic resonance metabolic imaging. Such molecular imaging applications require nuclear ... Sep 6, 2023 ... ... hyperpolarization-activated inward currents (h-currents). Using an electrical circuit model we investigated how h-currents can modulate the ...