What is the role of AMPK in cardiac hypertrophy?

Apr 1, 2016 ... In this review, we provide a comprehensive summary of both indirect and direct AMPK activators and their modes of action in relation to the structure of AMPK. AMPK activation positively regulates signaling pathways that replenish cellular ATP supplies, including fatty acid oxidation and autophagy. Jun 14, 2013 ... Effects of Acetyl-L-carnitine Supplementation on AMPK-Activity and ... AMPK-Activity and Mitochondrial Biogenesis in. LKB1 Knockout Mice. AMPK switches on catabolic pathways that generate ATP and switches off ATP ... AMPK activation on HSC has not been established. Aim of this study was ... Jan 25, 2022 ... AMPK acts as a tumor suppressor. However, following the onset of cancer, AMPK has been shown to either suppress or promote cancer, depending on cell type or ... Jun 25, 2024 ... Metformin significantly reduces HHV-6A-mediated glycolytic activation and impairs mTOR signaling, and then inhibits virus propagation. AMP-activated protein kinase (AMPK) is a highly conserved sensor of energy metabolism that can also control several cellular housekeeping functions. Apr 17, 2024 ... Our data demonstrate that PMF reduction in the intestine is sufficient to initiate locomotor responses to acute food deprivation. Dec 4, 2023 ... Research has shown that FLCN is involved in a lot of different cellular processes and the pathways involved are actually very complex. Jul 31, 2024 ... AMPK phosphorylation of β-arrestin-1 Ser330 potentiated PDE4 expression and activity, thereby inhibiting β-AR/cAMP/PKA activation.