What is the involvement of AMPK in parasitic infections?

AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease. Evidence here reveals that the rapid growth and proliferation of cancer cells lacking the tumor suppressor LKB1 is due to reduced activity of AMPK. Jan 25, 2022 ... AMPK acts as a tumor suppressor. However, following the onset of cancer, AMPK has been shown to either suppress or promote cancer, depending on cell type or ... Sep 10, 2020 ... Metformin treatment of primary hepatocytes and intact murine liver requires AMPK regulation of both RAPTOR and TSC2 to fully inhibit mTORC1, and ... Apr 1, 2016 ... In this review, we provide a comprehensive summary of both indirect and direct AMPK activators and their modes of action in relation to the structure of AMPK. Jun 14, 2013 ... Effects of Acetyl-L-carnitine Supplementation on AMPK-Activity and ... AMPK-Activity and Mitochondrial Biogenesis in. LKB1 Knockout Mice. AMPK has been shown to mediate the metabolic effects of hormones such as leptin, ghrelin, adiponectin, glucocorticoids and insulin as well as cannabinoids. Dec 4, 2023 ... Research has shown that FLCN is involved in a lot of different cellular processes and the pathways involved are actually very complex. Apr 1, 2019 ... A compound that is turning out to be one of the major metabolic regulators in the liver, skeletal muscle, fatty acids, and the brain. Jun 2, 2016 ... The present study reports that AMPK α1 containing AMPK complexes account for the vast majority of both basal and VEGF-A-stimulated AMPK activity ...