What is the involvement of AMPK in the regulation of mitophagy?

Feb 26, 2020 ... AMPK plays a crucial role in regulating Zika virus replication - a study from our lab published recently in the Journal of Immunology. Apr 17, 2024 ... Our data demonstrate that PMF reduction in the intestine is sufficient to initiate locomotor responses to acute food deprivation. Dec 4, 2017 ... AMPK maintains the energy balance by decreasing the ATP-consuming processes such as transcription of synthetic fat genes and rRNA, the translation of ribosomal ... AMPK activity is diminished in adipose tissue of very obese insulin-resistant people, in whom it is associated with increases in oxidative stress and more ... AMP-activated protein kinase (AMPK) is a highly conserved sensor of energy metabolism that can also control several cellular housekeeping functions. AMPK is an important sensor of decreased energy charge in cells and subsequently acts to increase catabolic reactions and decrease anabolic reactions. PGC-1α is ... Jan 23, 2021 ... The active constituent in ashwagandha, withaferin A, has been shown to increase AMPK levels and trigger the process of autophagy. ... This ... The phospho-AMPK (Thr172) kit is designed for robust cell-based quantification of AMP-activated protein Kinase modulation when phosphorylated on Threonine 172. Feb 24, 2025 ... ( A ) Representative traces of WT BSM contraction in response to EFS ( n = 4) before (blue) and after (red) exposure to AMPK inhibitor ... Our data indicate that metformin induces ALL cell death by triggering ER and proteotoxic stress and simultaneously down-regulating the physiologic UPR response.