What is the involvement of AMPK in the regulation of gene expression?

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1 ... We recently demonstrated that the LKB1 tumour suppressor kinase, ... Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. Overall, our findings indicate that AMPK plays a vital role in modulating WAT browning in response to thermal, nutritional and pharmacological cues, supporting ... Aug 22, 2022 ... In this video, Professor Keith Baar explains how the mTOR and AMPK molecular pathways get activated and their role in the interference ... AMPK, when activated in the brain's hypothalamus by the hunger hormone ghrelin, increases appetite and consequently weight gain. Whereas AMPK released in the ... Sep 10, 2020 ... Metformin treatment of primary hepatocytes and intact murine liver requires AMPK regulation of both RAPTOR and TSC2 to fully inhibit mTORC1, and ... PLIN2 phosphorylation is AMPK dependent. (A) Total cell lysates from. Display full size. To identify the kinase(s) behind this lipolysis-induced PLIN2 ... Dec 15, 2023 ... Together, these results demonstrate that AMPK activation by GSK621 elicits traits of immunogenic cell death and promotes a robust immune ... Apr 1, 2019 ... A compound that is turning out to be one of the major metabolic regulators in the liver, skeletal muscle, fatty acids, and the brain. 5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular ...