What are the patents related to acylation technologies? What are the current trends in acylation research and applications?

Jun 11, 2021 ... Two cavities connect at the active site, enabling acylation of Hedgehog in the lumen of the endoplasmic reticulum by lipid substrates from the ... The Friedel-Crafts Alkylation may give polyalkylated products, so the Friedel-Crafts Acylation is a valuable alternative. The acylated products may easily be ... May 17, 2018 ... In this post, we'll cover two important C–C bond-forming electrophilic aromatic substitution reactions which bear the names of their discoverers, Charles ... What is S-acylation? S-acylation is the post-translational addition of fatty acids to protein cysteine residues though a thioester bond. Importantly, and unlike ... S-acylation, commonly known as S-palmitoylation, is a reversible posttranslational lipid modification in which fatty acid, usually palmitic acid, ... Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, ... eLife assessment. This paper makes a valuable contribution by implicating S-acylation of Cys-130 in recruitment of the inflammasome receptor NLRP3 to the ... Thus, while the Friedel-Crafts acylation of benzene requires aluminum chloride as a catalyst, ferrocene can be acylated by acetic anhydride under milder ... Mar 22, 2025 ... The presence of a signal with hydroxylamine (+HA) treatment indicates that fatty acids are attached to the protein via a thioester bond. These ... May 4, 2021 ... We previously reported the development of ultra-long-acting fatty diacid acylated insulin analogs (hereafter ultra-long insulin analogs) for oral use.