What are the interdisciplinary aspects of acylation research?

Auto-S-fatty acylated proteins represent a new class of potential drug targets, which often harbor lipid-binding hydrophobic pockets and reactive cysteine ... ... acylation of the amino and alcohol radicals of the starting material. This reference teaches that ease of acylation follows the descending order: primary ... S-acylation results from the enzymatic addition of long-chain lipids, most typically palmitate, onto intracellular cysteine residues of soluble and ... The reaction is named after the French chemists Charles Friedel and James Crafts who discovered it in the late 19th century. The process involves three main ... Nov 15, 2023 ... Due to segregation from Golgi localised thioesterase enzymes caused by a nigericin induced breakdown in Golgi trafficking, NLRP3 becomes ... In combination with one of the strong acylating agents, the nucleophilic amines with no NH bonds undergo a fast acylation reaction that gives a cationic acyl ... Feb 11, 2025 ... What Is Acylation In Organic Chemistry? In this informative video, we will dive into the fascinating world of acylation in organic chemistry ... The most reactive substance containing an acyl group is an acyl chloride (also known as an acid chloride). These have the general formula RCOCl. Benzene is ... ... acylation: structural information from theory and experiment. Hui Zhu. Dept. of Chemistry and Biochemistry, University of California, Merced, USA. Search ... Log In. acylate. verb. ac·​yl·​ate ˈa-sə-ˌlāt. acylated; acylating. transitive verb. : to introduce an acyl radical into. acylation. ˌa-sə-ˈlā-shən. noun ...