How does the basicity of the nucleophile affect acylation? What are the leaving group abilities in acylation?

Apr 25, 2016 ... Acylation is the general term for substitution of acyl group, R-CO- on amino or hydroxyl group of an organic acid whereas acetylation is the ... What is S-acylation? S-acylation is the post-translational addition of fatty acids to protein cysteine residues though a thioester bond. Importantly, and unlike ... Dec 29, 2022 ... Protein acylation is involved in key cellular processes relevant to physiology and diseases, such as protein stability, protein subcellular localization, ... Feb 10, 2025 ... Mapping anthocyanin acylation and glycosylation loci. A) GWAS for anthocyanin acylation expressed as % of acylated anthocyanin (over total ... acylation Add to list Share · acylation · the "acylation" family. 2 million people are mastering new words. Master a word. Sign up now (it's free!) Sep 15, 2021 ... While the enzymology of protein fatty acylation is fascinating on its own, an equally compelling issue is: what is the functional significance ... Sep 20, 2023 ... ... acylation. The reactive electrophile is a resonance-stabilized acyl cation, generated by reaction between the acyl chloride and AlCl3 ... This reaction uses the acetyl chloride, CH3COCl, as the acylating agent and the compound called aluminium chloride, AlCl3 as the catalyst. In Friedel-Crafts ... Nov 15, 2023 ... Due to segregation from Golgi localised thioesterase enzymes caused by a nigericin induced breakdown in Golgi trafficking, NLRP3 becomes ... demonstrated that N-terminal acylation by a C8-C10 chain positively affects the antimicrobial activity of compounds: modified peptides show rapid killing ...