What are some interesting facts about acylation? What are some examples of unexpected outcomes in acylation reactions?

Jan 22, 2023 ... Benzene is treated with a mixture of ethanoyl chloride, CH3COCl, and aluminium chloride as the catalyst. A ketone called phenylethanone is ... Sep 20, 2023 ... ... acylation. The reactive electrophile is a resonance-stabilized acyl cation, generated by reaction between the acyl chloride and AlCl3 ... Oct 10, 2021 ... A new study published in Developmental Cell investigates S-acylation of the SARS-CoV-2 S protein. S-acylation, commonly known as S-palmitoylation, is a reversible posttranslational lipid modification in which fatty acid, usually palmitic acid, ... The reaction is named after the French chemists Charles Friedel and James Crafts who discovered it in the late 19th century. The process involves three main ... S-acylation results from the enzymatic addition of long-chain lipids, most typically palmitate, onto intracellular cysteine residues of soluble and ... Sep 18, 2024 ... Acylation is a chemical reaction in which an acyl group (RCO-) is introduced into a molecule. The acyl group contains a carbonyl group (C=O) ... Acylation is another important electrophilic reaction for the substitution of arenes. The electrophilic reagent, an acyl cation, is stabilized by resonance. A novel bioluminescence-based method to investigate uptake of bile acids in living cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2018; 315:G529-G537 eLife assessment. This paper makes a valuable contribution by implicating S-acylation of Cys-130 in recruitment of the inflammasome receptor NLRP3 to the ...