What are some illustrative examples of acylation reactions for students? What are some challenging acylation problems in organic synthesis?

The mechanism of this reaction is electrophilic substitution. Acyl halides and anhydrides of carboxylic acids are also commonly used acylating agents to acylate ... The most reactive substance containing an acyl group is an acyl chloride (also known as an acid chloride). These have the general formula RCOCl. Benzene is ... The reaction is named after the French chemists Charles Friedel and James Crafts who discovered it in the late 19th century. The process involves three main ... Aug 8, 2023 ... Our studies show that S-acylation of Frizzled receptors is a mechanism controlling their localization and function. Apr 25, 2016 ... Acylation is the general term for substitution of acyl group, R-CO- on amino or hydroxyl group of an organic acid whereas acetylation is the ... Feb 19, 2024 ... S-acylation, a lipid modification, is emerging as a key regulator of calcium handling proteins, altering their conformation and interactions ... Sep 18, 2024 ... Acylation is a chemical reaction in which an acyl group (RCO-) is introduced into a molecule. The acyl group contains a carbonyl group (C=O) ... Acylation is another important electrophilic reaction for the substitution of arenes. The electrophilic reagent, an acyl cation, is stabilized by resonance. Oct 10, 2021 ... A new study published in Developmental Cell investigates S-acylation of the SARS-CoV-2 S protein. Aug 22, 2024 ... What is the right way to create a topology for the protein with an acylated amino acid (serine acylated with palmitic acid)? It seems to be complicated for me.