What are peptidomimetics with acyl modifications?

Jun 5, 2015 ... Two enzyme families using phenolic compounds govern the acylation of secondary compounds in vascular plants: BAHD-acyltransferases (BAHD-ATs), ... You can first prepare the corresponding aryl ketone by the Friedel-Crafts acylation and then reduce the carbonyl to the alkyl group. Nov 2, 2020 ... O acylation is a type of acylation process in which the final product contains an oxygen atom, connecting the acyl group to the reactant ... Thus, while the Friedel-Crafts acylation of benzene requires aluminum chloride as a catalyst, ferrocene can be acylated by acetic anhydride under milder ... Feb 9, 2023 ... ... acylation on human and monkey epithelial cells infected with SARS-CoV-2. Their findings were recently published in the Journal of Lipid ... by way of acylation with simple achiral acylating agents. Based on the experimental results observed, a transition state (TS) model involving π-interactions ... An important caveat for all approaches that involve the incorporation of fatty acids is that more than just lysines can be fatty acylated. Cysteine ... Acylation refers to the addition of an acyl group to an organic molecule. An acyl group contains a carbonyl group (carbon-oxygen double bond) attached to ... Sep 5, 2020 ... Acylation or Friedel Crafts acylation is an example of Electrophilic Aromatic Substitution.The electrophile is CH3CO+ and is generated using ... A novel bioluminescence-based method to investigate uptake of bile acids in living cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2018; 315:G529-G537