What is CRISPR-Cas9? What are the ethical considerations of gene editing?

Mar 5, 2021 ... Mutations have many possible causes. Some mutations seem to happen spontaneously without any outside influence. They can occur when mistakes are made during ... ... mutations that render the cell with growth and survival advantages. In addition to the loss of function that a mutation in TP53 may cause, many p53 mutants ... Sep 12, 2024 ... JAK2 mutations lead to health conditions, including myeloproliferative neoplasms (MPNs), a type of blood cancer. Many people with MPNs have a JAK2 mutation. Genetic testing can identify gene mutations known to cause MEN1. In up to 1 in 4 cases, the test may not find a mutation even though you may be showing signs of ... Feb 20, 2025 ... Mutations are abnormal changes in the DNA of a gene and can sometimes lead to cancer. Find out common causes. Causes. Thalassemia is caused by mutations in the DNA of cells that make hemoglobin — the substance in red blood cells that carries oxygen throughout your body. The two genes could be the same mutation, or you could have two different ones. The specific mutations and combination you have is known as your 'genotype'. Mar 11, 2021 ... In a recent breakthrough, researchers have been able to calculate when the JAK2 mutation that causes MPN disease first appeared in two ... ... causes and presentations. Mitochondrial disease may be caused by genetic mutations in the body's nuclear DNA (the DNA found in the nucleus of cells) or by ... Oct 16, 2023 ... Let's explore some of the common causes of mutations, which can include everything from external factors like UV radiation and viruses to internal errors ...