How do mutations affect the evolution of regulatory elements? What are enhancers and silencers?

Mar 22, 2021 ... d The average probability of each mutational signature to have caused the KRAS mutation in a tumor sample. This value accounts for the level of ... Mar 6, 2017 ... Since the child's parents are only carriers of a mutation in the SLC26A4 gene, there are no health implications for them. Couples who are ... May 15, 2013 ... Although genetic factors contribute to congenital heart disease, new research shows that about 10 percent of these defects are caused by genetic ... Researchers identified a gene on the X chromosome that, when flawed (mutated), causes Duchenne, Becker, and an intermediate form of muscular dystrophies. Apr 23, 2019 ... What are the behavioral and lifestyle factors that cause cancer? A handful of behavioral factors may lead to genetic mutations and cancer ... Mar 31, 2021 ... Lung cancer occurs when gene mutations cause unusual cell growth in the lungs. Around 5–10% of these mutations are inherited, according to the National Cancer ... All blood cancers are caused by faults in our DNA (mutations). In practically all cases these changes to our DNA happen for reasons we can't explain. Mar 19, 2019 ... The purpose of this article is to highlight the many harmful villains, called mutagens that cause mutations, and how we can protect our bodies from harm. This can happen because cancer cells have changed, or “mutated.” Mutations can cause resistance to certain hormone therapies. An ESR1 mutation is a common ... Oct 9, 2020 ... Here we explain how mutations often arise when the cell makes mistakes as a transcriber, spell-checker, and pair of magnets.