What is class switch recombination?

PPP3CA Gene Mutations Cause a Severe Neurodevelopmental Disease and Seizures ... De novo mutations in the PPP3CA gene lead to a severe form of neurodevelopmental ... Recently, researchers discovered a new gene, GANAB, that is believed to cause polycystic liver and kidney disease as well. Mutations of the first gene, PKD1, ... Nov 8, 2019 ... Cancer is caused by mutations in our DNA that allow cells to grow uncontrollably – and eventually invade surrounding tissue. Mar 31, 2021 ... Lung cancer occurs when gene mutations cause unusual cell growth in the lungs. Around 5–10% of these mutations are inherited, according to the National Cancer ... Jan 19, 2022 ... There are multiple mutations that are linked to the development of this type of blood cancer, however the most common cause of this cancer is a ... This mutation leads to hyperactive JAK (Janus kinase) signaling, causing the body to make the wrong number of blood cells. CALR Nearly a quarter (23.5%) of ... Apr 23, 2019 ... What are the behavioral and lifestyle factors that cause cancer? A handful of behavioral factors may lead to genetic mutations and cancer ... MD is caused by mutations (alterations) in the genes responsible for healthy muscle structure and function. The mutations mean that the cells that should ... Jan 1, 2008 ... This study identifies two new mutations, confirms SCN4A as a common cause of paramyotonia congenita in the UK, and suggests further allelic ... Genetic Causes of Epilepsy. A mutation in a person's genes can put him or her at risk of developing epilepsy. Often, these are the genes that control the ...