What are the resources available for patients and families affected by B cell disorders?

Jan 17, 2025 ... Cutaneous B-cell lymphoma is a cancer that starts in the white blood cells and attacks the skin. It often causes a lump or group of lumps on the skin. Feb 15, 2024 ... About 1 out of 5 lymphomas in the United States is a follicular lymphoma. This is usually a slow-growing (indolent) lymphoma, although some follicular ... Apr 12, 2024 ... Current WHO B cell lymphoma classification features the following major updates (Int J Lab Hematol 2017;39:14): Newly defined high grade B cell lymphomas. The B Cells have the ability to transform into plasmocytes and are responsible for producing antibodies (Abs). Thus, humoral immunity depends on the B Cells ... This type of activation produces memory and plasma B cells. Naïve B cells bind to soluble or membrane bound antigens and internalize the antigen. The B cell ... Dec 23, 2015 ... Abstract. B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies ... Dec 1, 2018 ... The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas. Thus, CD40L/CD40 and MHC class II/T cell receptor (TCR) interactions are essential for peripheral B cell tolerance. The decreased numbers of CD4+ regulatory T ( ... B cells are essential for efficient immune responses and the maintenance of health. However, accumulating evidence points to the involvement of B cells in the ... ... B cells might play a critical role in disease pathogenesis. B cells and their antibodies have undisputed roles in health and disease within the airway ...