What are the potential therapeutic strategies targeting B cells in non-lymphoid hematological cancers?

A lymphocyte is a type of white blood cell that is part of the immune system. There are two main types of lymphocytes: B cells and T cells. Mar 10, 2021 ... ... switching. Neuritin reduced differentiation of mouse and human GC B cells into plasma cells, downregulated BLIMP-1, and upregulated BCL6. B cells are essential for efficient immune responses and the maintenance of health. However, accumulating evidence points to the involvement of B cells in the ... Controversies Conference on Therapies Targeting B Cells in Immune-Mediated Kidney Diseases ... The goal of this KDIGO conference is to review the efficacy and ... Jan 4, 2024 ... 10:07 Go to channel Understanding Diffuse Large B-Cell Lymphoma with Bruce Cheson, MD, FACP, FAAAS, FASCO Lymphoma Research Foundation This type of activation produces memory and plasma B cells. Naïve B cells bind to soluble or membrane bound antigens and internalize the antigen. The B cell ... ... B cells might play a critical role in disease pathogenesis. B cells and their antibodies have undisputed roles in health and disease within the airway ... Epigenetics is the study of changes in gene activity that are heritable but not caused by changes in the DNA sequence. By modulating gene activities, ... In this study, we have shown that EAE disease initiation and progression are differentially influenced by the depletion of B cells from mice with otherwise ... Apr 3, 2017 ... These immune tolerance mechanisms function at various stages of B cell development. Central tolerance refers to the regulatory mechanisms that ...