How do B cells respond to stress signals?

... B cells might play a critical role in disease pathogenesis. B cells and their antibodies have undisputed roles in health and disease within the airway ... Dec 18, 2020 ... B cells can directly present tumor-associated antigens to T cells or produce antibodies that increase antigen presentation to T cells or kill tumor cells. Rate of New Cases and Deaths per 100,000: The rate of new cases of diffuse large B-cell lymphoma was 5.6 per 100,000 men and women per year. The death rate was ... What is primary mediastinal large B-cell lymphoma? Primary mediastinal large B-cell lymphoma (PMBCL) is a type of non-Hodgkin lymphoma (NHL). It is sometimes ... B-cell lymphoproliferative disorders are conditions in the blood involving uncontrolled growth of white blood cells, also called lymphocytes. These conditions ... Feb 7, 2025 ... Researchers explore the role of B cells in non-lymphoid tissues, revealing new insights into infections, cancer, potential therapeutic breakthroughs. Feb 21, 2025 ... A framework, Mal-ID (machine learning for immunological diagnosis), to interpret the variable sequences of B and T cell receptors (BCRs and TCRs) from human ... Thus, CD40L/CD40 and MHC class II/T cell receptor (TCR) interactions are essential for peripheral B cell tolerance. The decreased numbers of CD4+ regulatory T ( ... Apr 21, 2015 ... To date, two models of Breg cell development can be suggested. The first is that Breg cells, similar to thymus-derived Treg cells, are a ... When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or ...