What are bispecific antibodies targeting B cells?

As a result, VA expanded chronic lymphocytic leukemia to include all chronic B-cell leukemias as related to exposure to Agent Orange or other herbicides during ... When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or ... A lymphocyte is a type of white blood cell that is part of the immune system. There are two main types of lymphocytes: B cells and T cells. DLBCL is a common type of fast growing (high grade) NHL. Lymphoma develops when white blood cells called lymphocytes grow out of control. The DURAClone IM B Cell panel allows for identification of late maturation stages of B cells, such as transitional stage, isotype class-switch, naïve and memory ... Feb 7, 2025 ... Researchers explore the role of B cells in non-lymphoid tissues, revealing new insights into infections, cancer, potential therapeutic breakthroughs. In B-cell lymphoma, some lymphocytes are no longer healthy and do not fight infection. Instead, they grow out of control, crowding out the normal cells and ... B-cell lymphoproliferative disorders are conditions in the blood involving uncontrolled growth of white blood cells, also called lymphocytes. These conditions ... Dec 1, 2018 ... The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas. Feb 11, 2025 ... Exhausted B cells may reduce flu vaccine effectiveness. Poor flu vaccine responses in people with immature and exhausted memory B cells may ...