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What is the role of the mucus layer in protecting the gut, and how might its disruption lead to IBS symptoms?
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what causes ibs to start Informational
- What mechanisms are involved in gut repair, and how might their impairment lead to persistent IBS?
- How might its dysregulation be involved in IBS? Can changes in the gut's response to pancreatic polypeptide (PP) contribute to the onset of IBS symptoms by affecting satiety and motility?
- Are there any critical periods in early development when the gut microbiome is particularly vulnerable to disruption? Can the use of non-steroidal anti-inflammatory drugs (NSAIDs) contribute to the start of IBS in some individuals?
- Are there any other co-occurring conditions that might be related to the start of IBS? Can hormonal changes trigger the onset of IBS, particularly in women?
- What types of chemical stimuli are detected by these pathways, and how might altered sensitivity lead to IBS?
- Does childhood trauma increase the risk of developing IBS?
- Does a viral infection ever lead to IBS?
- Are there any dietary or lifestyle factors that can support gut healing? Can alterations in the gut's production of mucin, the main component of the mucus layer, contribute to the onset of IBS?
- What is glutamate?
- How might their dysregulation be involved in IBS? Can alterations in the gut's response to purines contribute to the onset of IBS symptoms by affecting inflammation and visceral sensitivity?
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