



What types of chemical stimuli are detected by these pathways, and how might altered sensitivity lead to IBS?
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what causes ibs to start Informational
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- Are there any critical periods in early development when the gut microbiome is particularly vulnerable to disruption? Can the use of non-steroidal anti-inflammatory drugs (NSAIDs) contribute to the start of IBS in some individuals?
- How might altered sensitivity contribute to IBS? Can alterations in the gut's production of nitric oxide contribute to the onset of IBS symptoms by affecting motility and inflammation?
- Are there any psychological factors that can contribute to the start of IBS? Is there a genetic predisposition to developing IBS?
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- Does a "leaky gut" potentially play a role in triggering IBS symptoms?
- What role do neuropeptides play in regulating gut function, and how might their dysregulation be involved in IBS?
- How might altered sensitivity contribute to IBS? Can changes in the gut's production of hydrogen gas contribute to IBS symptoms like bloating?
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