



How might their altered function contribute to IBS? Can alterations in the gut's production of spinal afferent nerves contribute to the onset of IBS symptoms by affecting pain perception?
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what causes ibs to start Informational
- How might altered sensitivity contribute to IBS? Can alterations in the gut's production of vasoactive intestinal peptide (VIP) contribute to the onset of IBS symptoms by affecting motility and secretion?
- How might its dysregulation be involved in IBS? Can changes in the gut's response to pancreatic polypeptide (PP) contribute to the onset of IBS symptoms by affecting satiety and motility?
- How do these pathways normally function, and how might increased sensitivity lead to IBS symptoms?
- How might these exposures affect the gut microbiome or immune system and potentially lead to IBS symptoms?
- Are there any conditions or exposures that can affect the function of the vagus nerve? Can changes in the production or action of serotonin in the gut contribute to the start of IBS?
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- What types of chemical stimuli are detected by these pathways, and how might altered sensitivity lead to IBS?
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