



how does the cell coordinate DNA repair with the resumption of replication to ensure complete and accurate duplication of the genome despite damage to the template
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what is a template in dna replication Informational
- how is the lagging strand template replicated in short discontinuous fragments
- how does the semi-conservative nature of DNA replication guarantee that each daughter cell receives one parental template strand and one newly synthesized strand
- how can we leverage our knowledge of dna replication and template vulnerabilities to develop more effective diagnostic or therapeutic strategies for these diseases
- how is the transition from pre-RC to active replication initiation regulated at the template
- what are the consequences of low fidelity replication of the template
- what is meant by semi-conservative replication in relation to the template
- what factors influence the processivity of dna polymerases
- what is telomerase and how does it use an RNA template to extend telomeres
- what is the balance between the need for high fidelity replication to maintain genome stability and the introduction of occasional errors to drive evolutionary adaptation based on changes in the template information
- what are the factors that determine the location and timing of origin firing along the dna template in different cell types and developmental stages
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