How are clinical trials for ED medications designed to minimize the placebo effect?

Viagra acts as a relatively specific vasodilator of the penile circulation that enhances prolonged muscle relaxation/vasodilation by inhibiting the action of ... May 25, 2022 ... Common side effects can include headaches and dizziness, rarer side effects include heart problems. Viagra side effects · sensitivity to light · muscle aches · heartburn · nose bleeding · flushed skin · problems falling asleep · tingling in the arms, feet, ... The most common side effects of VIAGRA: headache; flushing; upset stomach; abnormal vision, such as changes in color vision (such as having a blue color tinge) ... It is in the phosphodiesterase-5 inhibitor (PDE5-I) class of medications. This activity describes the indications, actions, adverse effects, and ... Aug 27, 2021 ... Both Viagra and alcohol lower blood pressure, so the combination could cause side effects such as dizziness and fainting. Apr 12, 2024 ... Recreational use of Viagra without erectile dysfunction is not safe. Risks include mild side effects, dangerous drug interactions and ... The present study was conducted to investigate the cytogenetic effects of sildenafil citrate in SWR/J mouse bone marrow cells. The erectile dysfunction drug has been linked to serious side effects, including vision and hearing loss, heart complications and melanoma. Although the cardiovascular effects of sildenafil reported in available randomized, controlled clinical trials were relatively minor, heart disease patients ...