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Apr 24, 2007 ... Herein, we identify the Kruppel-like factor 15 (KLF15) as an inhibitor of cardiac hypertrophy. Myocardial expression of KLF15 is reduced in ... Mar 26, 2024 ... In conclusion, GDF-15 correlated with the severity of HF and was independently associated with outcomes in patients with chronic HF. Our study ... Jun 5, 2014 ... Two novel biomarkers, osteoprotegerin (OPG), a protein of the tumour necrosis factor superfamily, and growth-differentiation factor 15 (GDF-15), ... May 14, 2023 ... Growth differentiation factor-15 (GDF-15) improves cardiovascular risk assessment, but its predictive utility in patients with cancer remains undefined. We present for the first time that total and intact GDF-15 levels are higher in NAFLD than in controls, particularly in NASH subjects and those with severe ... Feb 15, 2021 ... The observed elevation in skeletal muscle Klf15 may serve to activate compensatory metabolic programs to maintain homeostasis in the face of ... Feb 2, 2012 ... We review the physiology and pharmacology of two atypical fibroblast growth factors (FGFs)—FGF15/19 and FGF21—that can function as hormones. Conclusions. In these chronic patients with HF, GDF-15 is better correlated with markers of renal dysfunction than NT-proBNP. Since the prognostic value of ... Apr 14, 2020 ... Macrophage inhibitory cytokine-1 or growth differentiation factor-15 (MIC-1/GDF15) has been implicated as a potential serum biomarker in PC and other ... Oct 1, 2023 ... Conclusion. This work suggests that GDF15 may be a promising prognostic marker to predict response to standard chemoradiation therapy in NSCLC.
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