What is the potential for using CRISPR-Cas systems to study or modify ribosomes?

Jun 3, 2008 ... Orthogonal ribosomes (o-ribosomes), also known as specialized ribosomes, are able to selectively trans- late mRNA not recognized by host ... Apr 22, 2021 ... RIBOSOME REARRANGED. To help reach his goals, Badran has developed what's known as an “orthogonal translation” system, in which a cell contains ... Apr 8, 2014 ... Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, followed by ... Apr 29, 2024 ... ... they do. By investigating differences among ribosomes, we may be opening the door to drugs that target specific pathogenic bacteria […] Prokaryotes have ribosomes that are slightly smaller than eukaryotes. Prokaryotic cells have ribosomes made of 50-S and 30-S subunits. Both subunits are ... Jun 21, 2017 ... illustration of a ribosome translating proteins Ribosomes, which build a protein (black) from an RNA strand (blue), may specialize in making ... Jul 23, 2024 ... The "protein factories" of the cell, the ribosomes, consist of up to eighty components. Researchers at the Biozentrum of the University of ... Apr 21, 2025 ... ribosome ... ribosome, particle that is present in large numbers in all living cells and serves as the site of protein synthesis. Ribosomes occur ... Jan 12, 2021 ... Here, we show that Linezolid, a ribosomal-targeting antibiotic (RAbo), effectively blocked the course of a T cell-mediated autoimmune disease. Jun 23, 2022 ... Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. This article explains more about ...