What is the clinical significance of ribosome-targeting antibiotics?

Ribosome (Translation) — Role & Importance. The role of the ribosome in translation is to read the mRNA strand and to form bonds between the amino acids. Jun 3, 2008 ... Orthogonal ribosomes (o-ribosomes), also known as specialized ribosomes, are able to selectively trans- late mRNA not recognized by host ... Posted October 13, 2022 ... Ribosomes, also known as Palade granules, are organelles that are made up of both RNA and protein, whose function is to assist ... Mar 25, 2014 ... Most antibiotics attack bacteria by disabling their ribosomes, and the bacteria fight back with compensating mutations. Using X-rays ... Jan 31, 2025 ... The researchers discovered that ribosomes help each other when encountering difficulties, a process they refer to as 'ribosome cooperativity'. Feb 28, 2020 ... Researchers at Northwestern Engineering have developed a system that can rapidly create cell-free ribosomes in a test tube, then select the ribosome that can ... In this Perspective, we discuss ribosome heterogeneity, where ribosomes of distinct compositions may be present both within cells and across tissues. Jan 12, 2021 ... Here, we show that Linezolid, a ribosomal-targeting antibiotic (RAbo), effectively blocked the course of a T cell-mediated autoimmune disease. The tour is designed for users with at least a general familiarity with translation and the ribosome, such as students who have taken general biology ... In addition to their central functions in translation, ribosomes can adopt inactive structures that are fully assembled yet devoid of mRNA.