How does the act of translation affect mRNA turnover?

Mar 7, 2025 ... Ribosomes are not uniform—they have subtypes! This work challenges an age-old notion that Ribosomes are homogenous translators of RNA. As calculated in the fourth column of the table, and schematically in Figure 1, at a fast doubling time of 24 minutes the 72,000 ribosomes per cell represent ... In addition to their central functions in translation, ribosomes can adopt inactive structures that are fully assembled yet devoid of mRNA. Feb 19, 2015 ... When ribosomes encounter consecutive AAA codons they undergo an unusual 'sliding' movement and are unable to accurately produce proteins. Sep 28, 2023 ... Every living creature relies on ribosomes to “read” DNA's genetic instructions and make proteins and enzymes that do the work of life. Nov 23, 2024 ... In most bacteria, the most numerous intracellular structure is the ribosome which is the site of protein synthesis in all living organisms. All ... Five years ago, Yale scientists made a splash with the long-sought atomic structure of the large subunit of the ribosome, the protein-synthesizing factory ... Sep 13, 2019 ... I understand they are synthesized in the nucleolus, the center of the nucleus, but how exactly are they created? Abstract. Ribosomes are highly conserved macromolecular machines responsible for protein synthesis in all living organisms. Work published in the past year ... Nov 7, 2022 ... ... We believe that their role as assembly factors is crucial for rapid synthesis of new ribosomes., powered by Localist Event Calendar Software.