How can we develop strategies to combat antibiotic resistance that target ribosomes?

Apr 8, 2014 ... Mutations in some of the proteins that make ribosomes cause disorders characterized by bone marrow failure and anemia early in life, followed by ... Jul 23, 2024 ... The "protein factories" of the cell, the ribosomes, consist of up to eighty components. Researchers at the Biozentrum of the University of ... Feb 11, 2022 ... mRNAs together with ribosomes and RNA-binding proteins form RNA granules that are targeted to axodendrites for localized translation in neurons. Sep 14, 2021 ... In a new study, scientists in the lab of Sebastian Klinge provide the most detailed view of how human small ribosomal subunits are put together. Abstract. The ribosome is a large multifunctional complex composed of both RNA and proteins. Biophysical methods are yielding low-resolution structures of the ... In eukaryotes, ribosomes get their orders for protein synthesis from the nucleus, where portions of DNA (genes) are transcribed to make messenger RNAs (mRNAs). High-resolution structures of prokaryotic and eukaryotic ribosomes, including the ribosomes from pathogenic organisms, in complex with antibiotics; Structure ... Download scientific diagram | Ribosome-associated sORFs, lncRNAs and novel transcripts. (A) Among the annotated sORFs associated with ribosomes, ... Sep 19, 2022 ... The ribosome is an organelle cell, that is composed of protein and RNA, which helps in the conversion of genetic code into chains of amino acids ... Apr 21, 2025 ... ribosome ... ribosome, particle that is present in large numbers in all living cells and serves as the site of protein synthesis. Ribosomes occur ...